$156.63

Immune Trio

The Immune Trio bundle are three immunity supplements that work together to give you the best Immune protection. MegaMune, Megaviron and Megacidin work together to give your Immune system a boost. All three products are designed to help keep your immune system functioning properly.

MegaMune

MegaMune™ is a triple action formula that can help maintain a healthy immune response for any time of year. This daily supplement supports the immune system with some of its most basic, yet vital, functions like immune surveillance, and other aspects of a healthy immune response.

MegaViron

MegaViron™ is an unrivaled, rapid-acting immune supplement formulated with potent herbs with antioxidant properties for seasonal immune support. MegaViron™ is designed to be taken on an as-needed basis for maximum immune support whenever you need it most.

MegaCidin

MegaCidin™ is a robust, next-generation throat spray that contains a unique and potent combination of ingredients clinically proven to support overall immunity. MegaCidin™ harnesses the power of probiotic spores along with the highly effective botanical mixture, known as Biocidin®

Product SKU: RHT-SBNDL-IMMU-3 Product Categories: , , , Brand:

Description

The Immune Trio bundle are three immunity supplements that work together to give you the best Immune protection. MegaMune, Megaviron and Megacidin work together to give your Immune system a boost. All three products are designed to help keep your immune system functioning properly.

MEGAMUNE

Megamune At a Glance

The immune system operates with two arms: the innate and adaptive branches. The innate immune response is rapid and can occur within 4 hours of immune activation. However, innate immune reactions are not very specific and can affect our own tissue in the body! MegaMune™ is formulated with immune soothing ingredients to help maintain a healthy immune response.** For example, green tea extract promotes T-regulatory cells that help calm and balance the immune system.8 Other synergistic ingredients like selenium, sulforaphane, cranberry polyphenols, and pomegranate polyphenols can support the body’s natural detoxification process.9-12

The adaptive immune response, on the other hand, is slower to respond. However, when it is activated, it is extremely precise and thus much gentler on host tissues. MegaMune™ supports the adaptive immune response by promoting T-helper cell production, such as CD4+ and CD8+ cells.

The key to maintaining a healthy immune response is dictated by the gut microbiome which helps balance both adaptive and innate immunity. In fact, the gut is home to about 70% of immune cells and acts as the mother board of the entire immune system. The combination of green tea extract and fruit polyphenols were added to MegaMune™ in order to enhance microbial diversity within the powerful gut microbiome.

MegaMune™ provides robust immune support that targets the immune system both on the cellular level and within the microbiome to provide a solid immune foundation. Take MegaMune™ any time of the year to keep your body vibrant and strong no matter what the outside world throws at you!

MEGAVIRON

MegaViron At Glance

MegaViron™ is an unrivaled, rapid-acting immune supplement formulated with potent herbs with antioxidant properties for seasonal immune support. MegaViron™ is designed to be taken on an as-needed basis for maximum immune support whenever you need it most. This product was designed to support 3 key features of immunity: the surveillance system, clean-up crew, and de-escalation team. The herbal ingredients in MegaViron™ work synergistically to support the body’s detection and eradication processes within a healthy immune response.

SURVEILLANCE TEAM

The immune surveillance team consists of macrophages, white blood cells, T cells, and interferons, which help the body detect foreign matter. Supporting the immune surveillance team is necessary to maintaining a healthy immune response. MegaViron helps maintain a healthy immune response by promoting the surveillance team’s efforts in the body including support of the body’s detection and phagocytosis processes.1-4 Plus, MegaViron promotes interferons and white blood cells (WBC) function, two important groups of immune cells that act like watch dogs.4-6

CLEAN-UP CREW

There is also a need for a robust clean-up crew to help rapidly remove foreign matter from the system. For example, red ginseng and Reishi mushroom beta-glucans are known to promote macrophage and natural killer (NK) cell production.7,8 Macrophages locate foreign matter and impact how it spreads. NK cells, support the body’s process to rid itself of impacted cells. To reinforce the clean-up crew, olive leaf extract, curcumin and NAC work together to support the body’s natural process of deactivating enzymes to remove them as a potential source of energy for foreign matter.2,9-11

DE-ESCALATION TEAM

Within a healthy immune response is the process of de-escalation, which helps the body to calm itself after a healthy immune response to foreign matter. A de-escalation team supports the body’s process in easing tensions and promoting the restoration of balance in the body. Calming ingredients such as N-acteyl-cysteine (NAC), curcumin, sea buckthorn polyphenols, Boswellia serrata, Chinese skullcap, Tinospora cordifolia, Andrographis paniculata, and stinging nettle root can help support balance in the immune system.2,12-19 MegaViron is a triple action, fast-acting immune formula designed to support immune surveillance, ecacy, and balance whenever you need it the most. Take control of your health and gain peace of mind with this unique, comprehensive immune support formula.

MEGACIDIN

When you think of supporting your immune system, you may think of consuming fresh foods, getting adequate sleep, or taking oral supplements like vitamin C, zinc, or probiotics. But did you know that you can quickly stimulate your immune system by targeting the immune tissue in your mouth? The soft tissue in your mouth that composes the inside of your lips and cheeks is known as buccal tissue and is a vital component of overall immunity! In fact, buccal tissue is capable of sending rapid signals to other parts of the immune system in a matter of minutes.

Megacidin At a Glance

Compared to the deeper, more internal tissues, our mouths more frequently encounter the barrage of microbes present in the outside world. Luckily, our oral immune system is quick to respond and well-equipped to fend off foreign invaders. Saliva and buccal tissue are rich in immune cells, such as T lymphocytes and immunoglobulins, that remove pathogens before they have a chance to further invade our bodies.1 This oral immune system also sends messages to numerous other tissues in the body, preparing our internal defenses before the pathogen even arrives at these distant sites. This gives us an enormous head start in fighting infection!

In addition, the buccal mucosa contains special gateways, always known as microfold (M) cells, which allow certain molecules to enter the bloodstream, while simultaneously guarding against pathogens.2 While other mucosal sites in the gut, lungs, and urogenital areas also contain M cells, the buccal tissue is the most permeable. This means that it rapidly absorbs beneficial compounds like probiotics, herbs, and some nutrients.

MegaCidin™ is a robust, next-generation throat spray that contains a unique and potent combination of ingredients clinically proven to support overall immunity. MegaCidin™ harnesses the power of probiotic spores along with the highly effective botanical mixture, known as Biocidin®, to provide synergistic immune support for every climate and season.

The probiotics in MegaCidin™, Bacillus subtilis HU58 and Bacillus coagulans (SC-208), are scientifically shown to support a healthy immune system by reducing inflammatory cytokines and producing protective compounds like -defensin.3,4 Additionally, probiotic throat sprays are shown to support healthy oral immunity in children.5

MegaCidin™ also contains an herbal blend known as Biocidin® which includes milk thistle, echinacea, goldenseal, shiitake extract, white willow bark, garlic, grapeseed extract, black walnut, tea tree oil, oregano oil, and several others. Many of these healing plants have been used in traditional medicine for hundreds of years, yet their beneficial qualities have only recently been proven by modern scientific research.

Human clinical trials conducted with Biocidin® show that this botanical mixture can support the immune system in as little as 30 minutes after spraying into the mouth.6 In fact, a single dose of Biocidin® can support the production of one of the most important immunoglobulins, known as secretory IgA, or sIgA.6 This immunoglobulin is found on mucosal surfaces, such as the gut, saliva, and respiratory system, and acts as one of the first lines of defense within the immune system.

Indeed, the number of studies completed on each individual herb in Biocidin®, joined with overwhelming support from the functional medicine community, provides abundant evidence for the use of these herbs in supporting the body’s innate defense system. Combined with the immune-supporting functions of Bacillus subtilis HU58 and Bacillus coagulans SC-208, MegaCidin™ is a preferred, all-natural remedy for healthy immune function. Whether you’re traveling or staying home, just a few sprays a day is all it takes to have a healthier immune system.

Dosage Instructions

Megamune Dosing Instructions

Ages 12+: Take 3 capsules daily with or without food, or as directed by your healthcare practitioner. Children under 12 years of age, please consult with your healthcare practitioner.

MegaViron Dosing Instructions

Ages 12+: Take 3 capsules twice daily with or without a meal at the first sign of symptoms and continue taking every day for 15 days or until supply runs out. Finish the bottle even if symptoms subside within the first few days. Children under 12 years of age, please consult with your healthcare practitioner.

MegaCidin Dosing Instructions

Ages 5+: Spray 1-3 sprays towards the back of the mouth 2-3 times per day or as directed by your healthcare pratitioner.

Product Research

Megamune Research

1. RERKSUPPAPHOL S, ET AL.
A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children. Pediatr Rep. 2019;11(2):7954.
2. SCIENCE M, ET AL.
Zinc for the treatment of the common cold: a systematic review and meta-analysis of randomized controlled trials. CMAJ. 2012;184(10):E551E561.
3. HOMANN PR, BERRY MJ.
The influence of selenium on immune responses. Mol Nutr Food Res. 2008;52(11):12731280. doi:10.1002/mnfr.200700330
4. HUDSON J, VIMALANATHAN S.
Echinacea—A Source of Potent Antivirals for Respiratory Virus Infections. Pharmaceuticals (Basel). 2011;4(7):10191031.
5. JENSEN, G. S, ET AL.
Double-Blind Placebo-Controlled, Randomized Pilot Study: Consumption of a High-Metabolite Immunogen from Yeast Culture has Beneficial Eects on Erythrocyte Health and Mucosal Immune Protection in Healthy Subjects. The Open Nutrition Journal 2008, 2, 68-75.
6.MOYAD, ET AL.
Effects of a modified yeast supplement on cold/flu symptoms. Urol Nurs 2008, 28 (1), 50-5.
7. MOYAD, ET AL.
Immunogenic yeast-based fermentate for cold/flu-like symptoms in nonvaccinated individuals. J Altern Complement Med. 2010, 16 (2), 213-8.
8. CARMEN P. WONG, LINDA P. NGUYEN, SANG K. NOH, TAMMY M. BRAY, RICHARD S. BRUNO, EMILY HO.
Induction of regulatory T cells by green tea polyphenol EGCG. Immunology Letters, 2011; DOI: 10.1016/j.imlet.2011.04.009
9. LIANG, ET AL.
Sulforaphane Inhibits Inflammatory Responses of Primary Human T-Cells by Increasing ROS and Depleting Glutathione. Frontiers in Immunology. 2018; 9:2584.
10. BLUMBERG JB, ET AL.
Impact of Cranberries on Gut Microbiota and Cardiometabolic Health: Proceedings of the Cranberry Health Research Conference 2015. Advances in Nutrition: An International Review Journal. 2016;7(4).
11. ANHÊ FF, ET AL.
Apolyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice. Gut 2015;64:872–83.
12. LI Z, SUMMANEN PH, KOMORIYA T, ET AL.
Pomegranate ellagitannins stimulate growth of gut bacteria in vitro: Implications for prebiotic and metabolic effects. Anaerobe. 2015;34, 164–168.

MegaViron Research

1. WU W, ET AL.
Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry. Viruses. 2015;8(1):6.
2. HAN S, XU J, GUO X, HUANG M.
Curcumin ameliorates severe influenza pneumonia via attenuating lung injury and regulating macrophage cytokines production. Clin Exp Pharmacol Physiol. 2018;45(1):8493.
3. RERKSUPPAPHOL S, ET AL.
A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children. Pediatr Rep. 2019;11(2):7954.
4. RERKSUPPAPHOL S, RERKSUPPAPHOL L.
A Randomized Controlled Trial of Zinc Supplementation as Adjuvant Therapy for Dengue Viral Infection in Thai Children. Int J Prev Med. 2018;9:88.
5. MATHEW S, KUTTAN G.
Immunomodulatory and antitumour activities of Tinospora cordifolia. Fitoterapia. 1999;70(1):35-43.
6. BADAR, ET AL.
Ecacy of Tinospora cordifolia in allergic rhinitis. Journal of Ethnopharmacology. 2015; 96(3):445–449.
7. MCELHANEY JE, ET AL.
A placebo-controlled trial of a proprietary extract of North American ginseng (CVT-E002) to prevent acute respiratory illness in institutionalized older adults. J Am Geriatr Soc. 2004;52(1):1319.
8. CHEN ET AL., 2013,
Mushroom -glucan Supplement Reduces Upper Respiratory Infections and Improves Quality of Life in Healthy Volunteers with High Lifestyle Stress. Unpublished manuscript.
9. MICOL V, CATURLA N, PÉREZ-FONS L, MÁS V, PÉREZ L, ESTEPA A.
The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV). Antiviral Res. 2005;66(2-3):129136.
10. GEILER J, MICHAELIS M, NACZK P, ET AL.
N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus. Biochem Pharmacol. 2010;79(3):413420.
11.
N-acetylcysteine: A rapid review of the evidence for eectiveness in treating COVID-19. CEBM. University of Oxford. https://www.cebm.net/covid-19/n-acetylcysteine-a-rapid-review-of-the-evidence-for-eectiveness-in-treating-covid-19/. Published May 26, 2020. Accessed May 27, 2020.
12. LI BQ, FU T, DONGYAN Y, MIKOVITS JA, RUSCETTI FW, WANG JM.
Flavonoid Baicalin Inhibits HIV-1 Infection at the Level of Viral Entry. Biochemical and Biophysical Research Communications. 2000;276(2):534-538. doi:10.1006/bbrc.2000.3485.
13. LARMO P.
Effects of sea buckthorn berries on infections and inflammation: a double-blind, randomized, placebo-controlled trial. European Journal of Clinical Nutrition. 2007;62(9):1123-1130
14. LI Y, HE S, TANG J, ET AL.
Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF-B/MAPK Signaling Pathway. Evid Based Complement Alternat Med. 2017;2017:8248142
15. COON JT, ERNST E.
Andrographis paniculata in the treatment and prevention of upper respiratory tract infection (URTI): a systematic review of safety and ecacy. Focus on Alternative and Complementary Therapies. 2010;8(1):160-161.
16. FRANCIŠKOVIC M, ET AL.
Chemical Composition and Immuno-Modulatory Effects of Urtica dioica L. (Stinging Nettle) Extracts. Phytother Res. 2017;31(8):11831191.
17. KUMAKI Y, WANDERSEE MK, SMITH AJ, ET AL.
Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin. Antiviral Res. 2011;90(1):2232.
18. RÅDMARK O, SAMUELSSON B.
Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis. Biochemical and Biophysical Research Communications. 2010;396(1):105-110.
19. AMMON HP.
Salai Guggal – Boswellia serrata: from a herbal medicine to a non-redox inhibitor of leukotriene biosynthesis. Eur J Med Res. 1996;1(8):369370.

MegaCidin Research

1. BRANDTZAEG P.
Secretory immunity with special reference to the oral cavity. J Oral Microbiol. 2013;5:10.3402/jom.v5i0.20401.
2. KRAAN, ET AL.
Buccal and sublingual vaccine delivery. Journal of Controlled Release. 2014;190: 580–592.
3. BARON M.
A patented strain of Bacillus coagulans increased immune response to viral challenge. Postgrad Med. 2009;121(2):114–118.
4. GUO M, WU F, HAO G, ET AL.
Bacillus subtilis Improves Immunity and Disease Resistance in Rabbits. Front Immunol. 2017;8:354.
5. ANDALORO C.
Bacteriotherapy with Streptococcus salivarius 24SMB and Streptococcus oralis 89a oral spray for children with recurrent streptococcal pharyngotonsillitis: a randomized placebo-controlled clinical study. Eur Arch Otorhinolaryngol. 2019;276(3):879–887.
6. BELLAR, ET AL.
The Eects of a Botanical Blend on Post-Exercise Mucosal Antimicrobial Proteins J Athl Enhanc. 2018;7:5

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Reviews

Melissa M
Melissa MTexas
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"I have tried several probiotics. I have been using MegaSporeBiotic for 8 months now and I have seen an improvement in my skin. During the pandemic, I suffered from hormonal breakouts and some from wearing masks. After trying a lot of topical solutions, I was advised to focus on gut health. "
John M
John MLos Angeles
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"This product is not an option at my house, but a staple!. My personal opinion is, this is an amazing product, this company has many other great products that WORK and if you give this a try, after the first jar, you will not be sorry and you will so glad you did!"
Al Dear
Al DearGreenwich
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"This made a huge difference in my gastrointestinal system. I went from nearly daily pain in my abdomen and upset bowels two or three times a week, to normal. This stuff is amazing for me. I bought this to help heal my leaky gut. I have been working on this for a year and finally this product sealed the deal! I finally healed my gut and no longer have my food sensitivities."
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*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THESE PRODUCTS ARE NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.