Tributyrin-X Supplement


Tributyrin-X™ helps to Improve sleep, Increase energy, reduce bloating, and enhance microbiome diversity. Tributyrin-X™ is the ultimate postbiotic. Multi-modality gut-healing technology, including 99.9% pure tributyrin inside patent-pending PXRcap™ that protects it from the stomach. No smell. No additives. Non-GMO.

95% of customers that buy this product give it a 4 or 5-Star rating.

“Helping to reduce my GI symptoms and heal my microscopic colitis! Hooray!”

Marilee S. (WA, US) Tributyrin-X Review

How Does Tributyrin-X™ Help?

What is Tributyrin?  Tributyrin has been studied since the 1930’s and is naturally found in small amounts in butter. It’s possibly the most powerful digestive support offered on the market. The difference clinically between probiotics and prebiotics and tributyrin is massive.

And the results are shocking doctors:

  • Powerful leaky gut & tight junction support
  • Regulation of gut speed (motility)
  • Promotes microbiome diversity
  • Helps healthy mucosal layers
  • Supports proper immune system activity
  • Supports healthy mast cells and histamine levels
  • Supports healthy weight management

Scientists have been working to solve 2 Big Problems. First, Purity and second, how to protect it against stomach acid. Tributyrin-X revolutionary breakthroughs solve both…

What is Butyrate & How Does It Help?

Buyrate has many roles like an energy source for gut cells… but it is also:

  • Critical for tight junctions (and avoiding leaky gut)
  • Supports mucus pathways
  • Enhances gut-brain connection
  • Regulates immune function and inflammation
  • Gut motility and transient times
  • Healthy gene expression
  • Regulating energy metabolism (may reduce overeating)
  • Stabilize and encourage a healthy microbiome
  • Protects against alcohol damage in the gut

Butyrate is the most abundant of the 3 short-chain fatty acids (SCFAs) created by bacteria fermentation of prebiotics and fibers in the colon.

Because of this scientists have termed butyrate supplements “Postbiotics”.

What’s a “Postbiotic” ?

A “postbiotic” is a new class of supplement that focuses on boosting Short Chain Fatty Acids (SCFAs) and their immense ability to help the body.

Butyrate is the most studied and most powerful of the 3 SCFA made by your intestines (acetate and propionate are the others).

SCFA are produced when the microbiome ferments prebiotics or fibers from food. However, when someone has a broken microbiome, chronic gut inflammation, or other gut conditions, then their ability to make SCFAs are reduced (1).

This is one of the big reasons why eating your vegetables is so important. Because if you can break down all that plant fiber it helps create SCFA (but if you can’t break it down, it’s bad news).


“First product that has given positive results over a long term. Most helpful!!”

Susan S. (AZ, US)

As most people with digestive upset know…


Taking extra fibers or prebiotics often doesn’t work… or sadly in some cases, they make digestion hurt worse.

And while probiotics are important and helpful… they just don’t seem as powerful as postbiotics.

Which makes taking a supplemental butyrate a really good idea to test… but not just any butyrate supplement will do…

Research suggests that tributyrin which has a different chemical makeup than bonded salts like sodium butyrate or magnesium butyrate or calcium butyrate is likely to be more easily used and more powerful. (2)


Why Tributyrin-X™ Works Better

Tributyrin-X™ is the best solution for butyrate supplementation because it’s packed with the most advanced technology no other butyrate supplement on the market can offer you:

  • 99.9% Pure Liquid Tributyrin – Professional Grade
  • Most Bioavailable Butyrate Type (tributyrin)
  • Revolutionary Patent-Pending PXRcap™ Softgel Delivery System
  • Non-GMO, Gluten-Free, Lactose-Free,
  • No Fillers, No Sterates, No Silicon Dioxide, No Charcoal
  • No smells, no burps, easy-to-swallow gel capsules
  • Up to a full 1,500mg a day serving size for 30 days

All of these factors combined make Tributyrin-X™ the ultimate butyrate supplement.

PXRcap™ studies show zero capsule leakage at 2 hours of simulated gastric acids.

And then it dissolves in 2.15 minutes after reaching the intestines… for perfect liquid tributyrin release.

How To Take Tributyrin-X

In human clinical studies, 300mg (3), 900mg (4), 1000mg (5), 1350mg (6), and 4,000mg (7) (8) a day have been used with really great safety and results.

Many clinicians we know use around 1,500 mg a day. And in certain cases higher amounts than that. However, EVERYONE should start slowly with one capsule a day 500mg, as each person’s gut integrity, motility and microbiome is different.

Each person’s effective dose can also be influenced by alcohol consumption, tobacco consumption, fat mass levels, speed of digestion (too fast might need more, too slow might need less), and other variables.

This means you start with 1 softgel a day and may take 1-3 gel capsules per day of Tributyrin-X or more as directed by your health provider.

Frequently Asked Questions

A: Tributyrin-X™ is for anyone looking for gut health support, inflammation support, immune system support, digestive comfort, metabolic support, over eating support, and microbiome support.

A: Animal studies suggest that the most powerful and potent form of butyrate is liquid Tributyrate. (9)

  • Tributyrate – liquid in various levels of purity (ours is measured at 99.9%)
  • Sodium butyrate – proprietary dried with bonding agents and powdered salt form
  • Calcium or Magnesium butyrate – proprietary dried and with bonding agents powered additives
  • Corebiome™ – proprietary form of dried tributyrate mixed with charcoals and other additives
  • Cyloc™ Tesserct – proprietary form of dried tribyurrate mixed with additives and binders

A: It’s been our experience you might notice results within days of starting Tributyrin-X™. If your body needs a higher dose you’ll know it when you get there. This may include less digestive pains, less bloating, easier bowel movements every morning like clock work, improvements in inflammation related issues, less cravings or less desire to eat as much food, ability to tolerate more foods in diet and more…

Some studies show that beneficial effects of butyrate still get stronger even after 12 weeks of usage.

Other human studies of 1 year (12 months) of usage showed users who stayed consistent and took it regularly had higher quality of life scores compared to placebo and less digestive upset relapses. (10)

So there appears to be an additive benefit to regularly taking butyrate containing supplements week-by-week, month-by-month.

A: No. Tributyrin-X™ does NOT contain Gluten, Dairy, Soy, Zero Sugar, and is GMO free.

A: Each bottle is good for 2 years from the date of manufacturing. An order placed today will be good for at least 18-20 months depending on that date.

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