Find Out How People Are Actually Reversing Autoimmune Disease And Getting Their Lives Back. Our microbiome plays a massive role in the training, stimulation, and regulation of our immune system. The more we learn about the functions of healthy gut microbes, we realized that a healthy microbiome is absolutely essential to a healthy, optimally-functioning immune system. In this episode, we discuss all the various ways that microorganisms within our gut are linked to various autoimmune conditions and other immune system dysfunctions.